Stephen Thomas BSc (Hons) Substack

Stephen Thomas BSc (Hons) Substack

Another Day, Another Study That Makes the Diet-Heart Hypothesis Look Rather Silly

Seed oil debate incoming!

the UK carnivore's avatar
the UK carnivore
Aug 14, 2025
∙ Paid

Well, well, well. Here we go again. Just when you thought the "saturated fat is the devil" brigade had run out of ways to ignore inconvenient data, along comes a gem from the archives that's been gathering dust since the 1970s. Today's featured performer: The Minnesota Coronary Experiment, a study so awkward for conventional nutrition wisdom that it took until 2016 for someone to properly dust it off and publish the full results. Spoiler alert: it doesn't end well for team seed oil.

The Simple Summary

Back in the late 1960s and early 1970s, researchers ran a proper randomized controlled trial on nearly 10,000 people. Half got a diet loaded with corn oil (high in linoleic acid), while the other half ate a diet higher in saturated fat. The corn oil group saw their cholesterol drop by nearly 14%, which should have meant fewer heart attacks and longer lives according to the prevailing wisdom.

Plot twist: More people in the corn oil group died. And when they looked at the hearts of those who …

User's avatar

Continue reading this post for free, courtesy of the UK carnivore.

Or purchase a paid subscription.
© 2025 the UK carnivore · Privacy ∙ Terms ∙ Collection notice
Start your SubstackGet the app
Substack is the home for great culture